Discover options

Explore health goals, tests & care options

Start with a health goal, then understand the tests, treatments, supplements and emerging compounds people compare, with status and evidence clearly explained. Save anything to My Journal to compare later.

Updated October 7, 2026

An unbranded white supplement jar beside a clear scoop of pink powder spilling out on a warm beige background.
Creatine monohydrateNo prescription · Supplement
A cropped hand rests on the trackpad of a silver laptop with a completely blank white screen, on a bright minimalist white desk; no face.
SemaglutidePrescription required · FDA-approved
A single foil blister pack of round white tablets angled on a bright white surface, clean studio light.
Magnesium glycinateNo prescription · Supplement
67 compounds

Semaglutide

medication

A GLP-1 medication that reduces appetite, approved for weight management and type 2 diabetes.

PrescriptionStrong human evidence
24 providers

Tirzepatide

medication

A weekly GIP and GLP-1 medication approved for weight management, sleep apnea and type 2 diabetes.

PrescriptionStrong human evidence
22 providers

Liraglutide

medication

An older, daily GLP-1 injection for weight management and diabetes, now available as a generic.

PrescriptionStrong human evidence
12 providers

An investigational triple-hormone weight-loss drug from Eli Lilly. Not approved; only available in trials.

Research onlyEmerging evidence
Education only

Metformin

medication

A cheap, decades-old diabetes pill that some people ask about for weight and healthy aging.

PrescriptionModerate human evidence
12 providers

Berberine

supplement

A plant compound sold as a supplement for blood sugar and weight. It is not a GLP-1 drug.

No prescriptionEmerging evidence
13 providers

BPC-157

peptide

A lab-made peptide popular for injury recovery. Mostly animal data, and not an approved drug.

Research onlyAnimal & lab studies only
Education only

TB-500

peptide

A synthetic fragment of thymosin beta-4 marketed for recovery. Animal data only; not approved.

Research onlyAnimal & lab studies only
Education only

A protein supplement made from animal collagen, popular for skin, joints and recovery.

No prescriptionEmerging evidence
14 providers

NAD+

supplement

A coenzyme every cell uses for energy; offered as IV drips and injections at longevity clinics.

Compounded prescriptionEmerging evidence
6 providers

NMN

supplement

An NAD+ precursor sold as a supplement. FDA confirmed in 2025 that it can be a supplement again.

No prescriptionEmerging evidence
7 providers

Epitalon

peptide

A four-amino-acid peptide marketed for aging and sleep. Limited research, not an approved drug.

Research onlyAnimal & lab studies only
Education only

MOTS-c

peptide

A peptide encoded by mitochondria, studied in mice for metabolism. Human data are minimal.

Research onlyAnimal & lab studies only
Education only

Rapamycin

medication

A transplant drug some clinicians prescribe off-label for longevity. Human aging data are early.

PrescriptionEmerging evidence
4 providers

Melatonin

supplement

The body's own sleep-timing hormone, sold as a supplement for jet lag and trouble falling asleep.

No prescriptionModerate human evidence
13 providers

A gentle form of magnesium that people take for sleep and relaxation.

No prescriptionEmerging evidence
15 providers

Glycine

supplement

A simple amino acid some people take before bed. Evidence comes from a few small studies.

No prescriptionEmerging evidence
9 providers

DSIP

peptide

A 1970s "sleep peptide" sold online. Human results were inconsistent and it is not approved.

Research onlyAnimal & lab studies only
Education only

Semax

peptide

A Russian nasal peptide marketed for focus. Approved in Russia, not in the US.

Research onlyAnimal & lab studies only
Education only

Selank

peptide

A Russian peptide marketed for anxiety and focus. Not approved or compoundable in the US.

Research onlyAnimal & lab studies only
Education only

L-theanine

supplement

An amino acid from tea leaves, often paired with coffee for calm focus.

No prescriptionEmerging evidence
12 providers

Fish and algae oils (EPA and DHA) taken for heart and brain health.

No prescriptionModerate human evidence
16 providers

GHK-Cu

peptide

A copper peptide common in skin-care serums. Injectable versions are not approved.

No prescriptionEmerging evidence
6 providers

Finasteride

medication

A prescription pill that slows male-pattern hair loss by lowering DHT.

PrescriptionStrong human evidence
9 providers

Minoxidil

medication

A hair-growth drug: topical over the counter, or a low-dose pill prescribed off-label.

PrescriptionStrong human evidence
19 providers

Tretinoin

medication

A prescription vitamin A cream for acne and sun-related skin aging.

PrescriptionStrong human evidence
10 providers

Prescription testosterone replacement for men with confirmed low testosterone.

PrescriptionStrong human evidence
7 providers

Enclomiphene

medication

A pill that can raise a man's own testosterone while preserving fertility. Compounded, not approved.

Compounded prescriptionModerate human evidence
6 providers

A reproductive-hormone peptide studied in fertility research. Restricted from compounding.

Research onlyEmerging evidence
Education only

Sermorelin

peptide

A peptide that prompts your pituitary to release growth hormone. Available compounded.

Compounded prescriptionEmerging evidence
7 providers

An FDA-approved growth-hormone-releasing peptide for belly fat in people with HIV.

PrescriptionModerate human evidence
1 provider

The most researched sports supplement, for strength and power; brain effects are being studied.

No prescriptionStrong human evidence
14 providers

Ipamorelin

peptide

A growth-hormone-releasing peptide sold online for body composition. Not approved.

Research onlyAnimal & lab studies only
Education only

CJC-1295

peptide

A long-acting growth-hormone-releasing peptide sold online, often with ipamorelin. Not approved.

Research onlyAnimal & lab studies only
Education only

Vitamin D

supplement

An essential vitamin for bones and muscles; worth testing before you supplement.

No prescriptionModerate human evidence
17 providers

Probiotics

supplement

Live microbes in supplements and foods. Benefits depend heavily on the specific strain.

No prescriptionEmerging evidence
17 providers

L-glutamine

supplement

An amino acid that fuels gut-lining cells; taken for "leaky gut" and recovery.

No prescriptionEmerging evidence
10 providers

Psyllium

supplement

A soluble fiber for regularity that also modestly lowers LDL cholesterol.

No prescriptionStrong human evidence
10 providers

An investigational long-acting amylin analog being studied alone and with semaglutide.

Research onlyEmerging evidence
Education only

An investigational glucagon and GLP-1 receptor agonist studied for obesity and liver disease.

Research onlyEmerging evidence
Education only

Mazdutide

peptide

A glucagon and GLP-1 receptor agonist approved in China but not approved in the US.

Research onlyEmerging evidence
Education only

An investigational amylin-receptor agonist being studied by Eli Lilly for obesity.

Research onlyEmerging evidence
Education only

AOD-9604

peptide

A modified growth-hormone fragment promoted for fat loss without an FDA-approved use.

Research onlyEmerging evidence
Education only

An FDA-approved prescription medicine also sold online as unapproved RUO material under PT-141.

PrescriptionModerate human evidence
2 providers

An FDA-approved implant for erythropoietic protoporphyria, distinct from online tanning products.

PrescriptionModerate human evidence
1 provider

An unapproved pigment-stimulating peptide sold online for tanning and sexual effects.

Research onlyAnimal & lab studies only
Education only

An FDA-approved medicine for Barth syndrome also sold online as unapproved SS-31.

PrescriptionModerate human evidence
1 provider

An immune-signaling peptide approved in some countries but not FDA-approved in the US.

Research onlyEmerging evidence
Education only

Tesofensine

medication

An investigational small-molecule weight-loss drug often grouped into RUO peptide catalogs.

Research onlyEmerging evidence
Education only

A prescription fertility hormone that is also misrepresented in RUO and weight-loss markets.

PrescriptionStrong human evidence
1 provider

Oxytocin

hormone

A hospital obstetric medicine also promoted in unapproved nasal and wellness products.

PrescriptionStrong human evidence
Ask a clinician

Cerebrolysin

medication

An injectable peptide mixture used in some countries but not FDA-approved in the US.

Research onlyEmerging evidence
Education only

IGF-1 LR3

peptide

A long-acting laboratory analog of IGF-1 with no FDA-approved human use.

Research onlyAnimal & lab studies only
Education only

Tadalafil

medication

A prescription pill for erectile dysfunction and an enlarged prostate (BPH), sold as Cialis and generics.

PrescriptionStrong human evidence
13 providers

Sildenafil

medication

The first prescription pill for erectile dysfunction, sold as Viagra and widely as a generic.

PrescriptionStrong human evidence
14 providers

Dutasteride

medication

A prescription prostate drug that lowers DHT, used off-label in the US for male pattern hair loss.

PrescriptionModerate human evidence
5 providers

Estradiol

hormone

The main estrogen used in menopause hormone therapy, as pills, patches, gels, sprays and vaginal forms.

PrescriptionStrong human evidence
15 providers

A prescription hormone that protects the uterine lining during estrogen therapy and supports fertility treatment.

PrescriptionStrong human evidence
12 providers

Synthetic thyroid hormone (T4), the standard prescription treatment for an underactive thyroid.

PrescriptionStrong human evidence
7 providers

Clomiphene

medication

A prescription fertility pill that helps trigger ovulation; also used off-label for men.

PrescriptionStrong human evidence
4 providers

Spironolactone

medication

A heart and blood pressure pill, also used off-label for hormonal acne and hair loss in women.

PrescriptionModerate human evidence
5 providers

Retinol

cosmetic

An over-the-counter vitamin A ingredient in skin care, a gentler and weaker cousin of prescription tretinoin.

No prescriptionModerate human evidence
9 providers

Ashwagandha

supplement

An Ayurvedic herb sold as a supplement for stress and sleep, with small trials and rare liver injury reports.

No prescriptionEmerging evidence
15 providers

A well-absorbed form of magnesium, sold as a supplement and as an over-the-counter laxative.

No prescriptionModerate human evidence
13 providers

Prebiotics

supplement

Fibers such as inulin, FOS and GOS that feed beneficial gut bacteria. Not the same as probiotics.

No prescriptionEmerging evidence
12 providers

Vitamin B12

supplement

An essential vitamin for nerves and red blood cells; low levels are common in older adults and metformin users.

No prescriptionStrong human evidence
16 providers

Iron

supplement

A mineral supplement for iron deficiency, best taken after a ferritin or blood test confirms a need.

No prescriptionStrong human evidence
16 providers