No. 053peptide

IGF-1 LR3

IGF-1 LR3 is a peptide that is research only, not approved for human use in the US.

Also known as Long R3 IGF-1, LR3-IGF-1

IGF-1 LR3 is a modified insulin-like growth factor designed for longer laboratory activity. It is not the FDA-approved IGF-1 medicine mecasermin and is sold online mainly through RUO vendors.

Macro shot of empty clear plastic tube tips standing in a bright blue and green laboratory tray.
Research only · Not for human use
Not approved for human useNot approved for human use in the US. We list it so you can learn what it is, but we do not link to anyone selling it. If you are considering it, a clinician can talk through approved alternatives.

Is IGF-1 LR3 legal in the US?

Not approved for human use in the US. We list it so you can learn what it is, but we do not link to anyone selling it. Not FDA-approved, not an approved compounded product and not interchangeable with prescription mecasermin.

As of September 28, 2026.

What does the evidence say about IGF-1 LR3?

Animal & lab studies only

Consumer muscle, recovery and anti-aging claims rely primarily on mechanism and nonclinical research.

What are the risks and side effects of IGF-1 LR3?

  • Not approved for human use. Products sold online as "research chemicals" are not made to drug standards, so identity, purity, sterility and dose are unverified.
  • IGF-1 activity can cause dangerous low blood sugar.
  • Growth signaling raises concerns for people with current or past cancer.
  • It can affect organs, soft tissue and fluid balance.
  • It is prohibited in tested sport.

What should you ask a clinician about IGF-1 LR3?

  • Is there a medical reason to measure or treat my IGF-1 level?
  • Could growth-factor exposure be risky with my cancer or glucose history?

These save with the compound when you add it to My Journal, so they’re on the printout for your visit.

Where can I get IGF-1 LR3?

IGF-1 LR3 is not approved for human use, so DiscoverMedica links to no seller.

We don’t link to sellers of research-only compounds. Products sold “for research use only” are not made for people and are not held to pharmaceutical quality standards.

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Sources

Educational information only, not medical advice. It does not replace a conversation with a licensed clinician.

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