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Goal · 09

Digestive & gut health

Bloating, digestion, regularity and microbiome support, including fiber, probiotics and related testing.

7 compounds: 6 over the counter, 1 research only.

Digestive health checklist Start My Journal

Updated October 7, 2026

An overhead arrangement of small bowls holding cracked wheat, quinoa, couscous, sunflower seeds, flaxseed and mung beans on a bright white background.

compounds for digestive & gut health, each with its US status

licensed providers list at least one of them

%

sold over the counter, no prescription needed

Buckwheat and rice grains piled on two dark spoons against a clean white background, shot close and bright.
Overhead shot of a yogurt bowl topped with blackberries, strawberries, granola and fresh mint on a bright pink surface.
Four bright, clean bowls of healthy meal-prep salads with greens, feta, avocado, chickpeas and corn, arranged on a white marble surface; no people visible.
A pale ceramic bowl of rolled oats spilling onto a plain grey surface beside a silver spoon, shot from above with generous negative space.
7 compounds

Berberine

supplement

A plant compound sold as a supplement for blood sugar and weight. It is not a GLP-1 drug.

No prescriptionEmerging evidence
13 providers

BPC-157

peptide

A lab-made peptide popular for injury recovery. Mostly animal data, and not an approved drug.

Research onlyAnimal & lab studies only
Education only

Probiotics

supplement

Live microbes in supplements and foods. Benefits depend heavily on the specific strain.

No prescriptionEmerging evidence
17 providers

L-glutamine

supplement

An amino acid that fuels gut-lining cells; taken for "leaky gut" and recovery.

No prescriptionEmerging evidence
10 providers

Psyllium

supplement

A soluble fiber for regularity that also modestly lowers LDL cholesterol.

No prescriptionStrong human evidence
10 providers

A well-absorbed form of magnesium, sold as a supplement and as an over-the-counter laxative.

No prescriptionModerate human evidence
13 providers

Prebiotics

supplement

Fibers such as inulin, FOS and GOS that feed beneficial gut bacteria. Not the same as probiotics.

No prescriptionEmerging evidence
12 providers