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No. 034peptide
CJC-1295
CJC-1295 is a peptide that is research only, not approved for human use in the US.
Also known as CJC-1295 DAC, CJC-1295 without DAC, Mod GRF 1-29
CJC-1295 is a modified version of growth-hormone-releasing hormone designed to last longer in the body. A drug company studied it in the 2000s, and it is now sold as a research peptide for body composition and recovery.
Not approved for human useNot approved for human use in the US. We list it so you can learn what it is, but we do not link to anyone selling it. If you are considering it, a clinician can talk through approved alternatives.
Is CJC-1295 legal in the US?
Not approved for human use in the US. We list it so you can learn what it is, but we do not link to anyone selling it. Not FDA-approved. Its 503A nomination was withdrawn and it was not part of the 2026 advisory committee review, so it is not on the bulks list and cannot be lawfully compounded.
As of September 23, 2026.
Key takeaways
- CJC-1295 is a long-acting version of growth-hormone-releasing hormone. It is not approved for human use.
- A small 2006 study showed it raises growth hormone and IGF-1 for days, but no trials test the benefits it is marketed for.
- FDA cited serious adverse events, including a raised heart rate and flushing or low blood pressure reactions.
- It is banned in sport, and there is no lawful compounding route.
How does CJC-1295 work?
Proposed from lab and animal studiesCJC-1295 copies the brain signal that tells the pituitary to release growth hormone, with a change that makes it last much longer in the blood. In a small study of healthy adults, growth hormone and IGF-1 stayed raised for days.
That study measured hormone levels, not muscle, fat or recovery. Claims about body composition come from animal work.
What does the evidence say about CJC-1295?
Animal & lab studies onlyA small 2006 human study showed it raises growth hormone and IGF-1, but there are no trials for the benefits it is marketed for.
Why are clinicians and regulators cautious about CJC-1295?
Regulators and sports medicine reviewers see CJC-1295 as an experimental hormone booster with limited human data and known reactions.
FDA says it has identified serious adverse events with CJC-1295, including a raised heart rate and whole-body vasodilation reactions, and that available clinical data are limited.
FDA: Bulk drug substances that may present significant safety risks (Category 2)A 2006 study in healthy adults found CJC-1295 produced prolonged rises in growth hormone and IGF-1.
Prolonged GH and IGF-I stimulation by CJC-1295 in healthy adults (2006)A 2026 review for sports medicine physicians notes muscle findings for CJC-1295 combined with other peptides are limited to animal studies.
Injectable peptide therapy: a primer for orthopaedic and sports medicine physicians (Am J Sports Med 2026)The WADA 2026 list names CJC-1295 as a prohibited growth hormone releasing factor.
WADA 2026 Prohibited List (PDF mirror)
Summaries of published guidelines, drug labels, regulators and reviews, each attributed to its source. DiscoverMedica does not employ clinicians.
Who should avoid CJC-1295?
Especially important to avoid if
- People with heart rhythm problems, given the raised heart rate FDA cited
- People with diabetes or prediabetes, since growth hormone can raise blood sugar
- Anyone with a current or past cancer
- Pregnancy or breastfeeding
- Competitive athletes in tested sport
What are the risks and side effects of CJC-1295?
- Not approved for human use. Products sold online as "research chemicals" are not made to drug standards, so identity, purity, sterility and dose are unverified.
- FDA noted reports of increased heart rate and vasodilation reactions (flushing, low blood pressure).
- Sustained growth hormone stimulation can raise blood sugar and cause water retention.
- Products labeled "with DAC" and "without DAC" are different molecules, and research sellers often mix them up.
What should you ask a clinician about CJC-1295?
- Should my growth hormone or IGF-1 actually be tested?
- What proven options fit my goal?
These save with the compound when you add it to My Journal, so they’re on the printout for your visit.
Where can I get CJC-1295?
CJC-1295 is not approved for human use, so DiscoverMedica links to no seller.
We don’t link to sellers of research-only compounds. Products sold “for research use only” are not made for people and are not held to pharmaceutical quality standards.
Compare and learn
CJC-1295: questions, answered
What does "with DAC" mean?
It refers to a chemical add-on that makes the peptide last longer. Products labeled with and without it are different molecules, and online sellers often mix them up.
Is there evidence it helps body composition?
Not in people. Human data are limited to hormone levels in a small study.
Can I get it from a telehealth provider?
No. CJC-1295 is not FDA-approved and has no lawful compounding route, so there is nothing a licensed telehealth provider can legitimately prescribe. If a site offers it, treat that as a warning sign. DiscoverMedica does not link to anyone selling it.
What does "research use only" mean?
It means the product is not made or tested for people. FDA has sent warning letters to sellers who use that label while making health claims, and says it judges a product by how it is marketed, not by the disclaimer.
Important safety information
CJC-1295 is not approved for human use in the US. Not approved for human use in the US. We list it so you can learn what it is, but we do not link to anyone selling it.
Key risks
- Not approved for human use. Products sold online as "research chemicals" are not made to drug standards, so identity, purity, sterility and dose are unverified.
- FDA noted reports of increased heart rate and vasodilation reactions (flushing, low blood pressure).
- Sustained growth hormone stimulation can raise blood sugar and cause water retention.
- Products labeled "with DAC" and "without DAC" are different molecules, and research sellers often mix them up.
Avoid it especially if
- People with heart rhythm problems, given the raised heart rate FDA cited
- People with diabetes or prediabetes, since growth hormone can raise blood sugar
- Anyone with a current or past cancer
- Pregnancy or breastfeeding
- Competitive athletes in tested sport
This is not a complete list of risks. Talk to a licensed clinician or pharmacist about your own situation. If you have a severe reaction, call 911. You can report side effects to the FDA through MedWatch at 1-800-FDA-1088.
Sources
- PubChem: CJC-1295 (CID 91971820)
- FDA: Bulk drug substances that may present significant safety risks (Category 2)
- Prolonged GH and IGF-I stimulation by CJC-1295 in healthy adults (2006)
Also checked for this guide
- FDA: 503A bulk drug substance categories list (May 14, 2026)
- WADA 2026 Prohibited List (PDF mirror)
- Injectable peptide therapy: a primer for orthopaedic and sports medicine physicians (Am J Sports Med 2026)
- USADA: Six things to know about peptide hormones
Guide reviewed September 23, 2026.
Educational information only, not medical advice. It does not replace a conversation with a licensed clinician.
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