Start with a health concern. Understand the options, compare them, and save what matters. Open My Journal
Start My Journal
DiscoverCompareLearnHow We VerifyMy JournalStart My Journal
Goal · 03

Sleep & stress

Sleep quality, stress, recovery and the established options people often consider first.

9 compounds: 6 over the counter, 3 research only.

Sleep & stress checklist Start My Journal

Updated October 7, 2026

A calm bedroom at dusk with sheer curtains, a softly glowing black table lamp and a blue vase of dried plants beside a cozy bed.

compounds for sleep & stress, each with its US status

licensed providers list at least one of them

%

sold over the counter, no prescription needed

A glass of water and a small bowl of blueberries on a wooden tray resting on soft grey bed linens in a calm, softly lit bedroom.
An ultra-minimal, bright white bedroom corner lit by soft window light.
A minimalist bright bedroom nightstand at dusk with a glowing white lamp and a pale blue ceramic knot sculpture, no people or text visible.
A bright, pastel-toned bedroom corner with a bedside lamp glowing beside a neatly made striped bed.
9 compounds

Epitalon

peptide

A four-amino-acid peptide marketed for aging and sleep. Limited research, not an approved drug.

Research onlyAnimal & lab studies only
Education only

Melatonin

supplement

The body's own sleep-timing hormone, sold as a supplement for jet lag and trouble falling asleep.

No prescriptionModerate human evidence
13 providers

A gentle form of magnesium that people take for sleep and relaxation.

No prescriptionEmerging evidence
15 providers

Glycine

supplement

A simple amino acid some people take before bed. Evidence comes from a few small studies.

No prescriptionEmerging evidence
9 providers

DSIP

peptide

A 1970s "sleep peptide" sold online. Human results were inconsistent and it is not approved.

Research onlyAnimal & lab studies only
Education only

Selank

peptide

A Russian peptide marketed for anxiety and focus. Not approved or compoundable in the US.

Research onlyAnimal & lab studies only
Education only

L-theanine

supplement

An amino acid from tea leaves, often paired with coffee for calm focus.

No prescriptionEmerging evidence
12 providers

Ashwagandha

supplement

An Ayurvedic herb sold as a supplement for stress and sleep, with small trials and rare liver injury reports.

No prescriptionEmerging evidence
15 providers

A well-absorbed form of magnesium, sold as a supplement and as an over-the-counter laxative.

No prescriptionModerate human evidence
13 providers
Example journals

Journals for sleep & stress.

A bright, clean bedroom corner at evening with a black table lamp glowing softly on a white nightstand beside a bed with blue and white pillows.
Marcus
Personal list
Example

My sleep reset

Starting with the gentle, well studied stuff before anything stronger.

Magnesium glycinateGlycineMelatoninL-theanine